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Genome editing is the new black
If you have been following the scientific media recently, I won’t blame you for thinking that these days nobody does anything else but genome editing, and that genome editing was invented yesterday. As...
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Single-cell sequencing comes of age
In August last year, Nick Navin wrote in a Genome Biology article: “In the near future, it might be possible to perform both genome and transcriptome sequencing on the same single cancer cell.”...
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#ICYMI: April’s biology research highlights
April has gone, but its highlights are here: canine health, antibiotic resistance, chromatin organization in the sperm nucleus, eukaryotic evolution, and more…
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Real-time genomic surveillance with nanopore-seq
Lessons about the epidemic control are usually learned the hard way. So what have we learned from the most recent outbreaks of Ebola and other diseases, and how can the most recent developments in...
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Molecular cut-and-paste method improves on pasting
An article in Genome Medicine reports on new means to increase efficiency of homology-directed DNA repair in CRISPR/Cas9 genome editing experiments.
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Genome editing: best invention since sliced bread
If PCR was in molecular biology the invention of the 20th century, genome editing tools are the invention of the 21st. This month Genome Biology takes a closer look at this promising but still very...
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Efficient genetic modification of the tomato genome: an author Q+A
Modifying plant genomes is still a challenge despite the recent advances in technology. Research published in Genome Biology set to develop more efficient methods, showing that they can be applied to...
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Generating attenuated malaria parasites with genome editing: an author Q+A
Today, Genome Biology published research investigating the success of using zinc-finger nucleases to create attenuated parasites for use in a vaccine. Here, co-authors Friedrich Frischknecht and Mirko...
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Cas9: one protein to rule them all
As we hail CRISPR/Cas as the most versatile, easy to design genome editing tool, as CRISPR in every form and color wins media attention, it is very easy to forget that the true workhorse in this system...
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Using CRISPR/Cas9 to genetically modify crops
Today, Genome Biology has published research describing crops genetically modified using genome editing technology. The researchers use CRISPR/Cas9 on both barley and Brassica, and here we ask the...
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